Mrs. Rodriguez is David Rodriguez's mother and co-owner of Nueva Familia with her husband, Mr. Rodriguez. She first appeared in the Season Nineteen episode, "You're Not Yelping".
In "You're Not Yelping", Mrs. Rodriguez is hard at work in her family's restaurant preparing meals for Eric Cartman, who is posing as a yelp critic in order to receive free food. Her husband, in a panic, asks her to rush two taco orders for Cartman.
After Whistlin' Willy's stands up to Gerald Broflovski's antics as a yelp critic, she and her husband become excited that they can finally stop giving these people excessive amounts of service. Unfortunately, this was short-lived as the yelp critics fought back against Whistlin' Willy's. She and her husband had decided to shut down the restaurant. The restaurant was later saved with David's plan to subtly retaliate against the yelpers.
Mrs. Rodriguez wears black shoes, blue pants, and a red shirt. She wears two bracelets, gold and green respectively, and teal hoop earrings. She has long, black hair.