Mankind's evolution begins to accelerate at a rapid and disturbing pace. Concurrently, another species on the planet is exhibiting the same drastic development. Eventually the two species will battle to the death and Faith Hilling may be humanity's only hope.
Afterwards, a news reporter is seen reporting on "faith hilling". He states that everyone is wondering when the first person will die from performing the meme. Later, the fourth grade class is lectured by Professor Lamont, who shows them a video detailing the dangers of performing memes.
After the end of the school day, the boys are shown wondering where they should "faith hill" next. However, Butters, traumatized by the aforementioned video, refuses to "faith hill". Shortly afterwards, Craig Tucker reveals that the boys made the front page of the newspaper due to their "faith hilling" the presidential candidate debate. After purchasing a newspaper, to their horror, they read that "faith hilling" has already become outdated, being replaced by "Taylor Swifting".
After coming to the mutual opinion that "faith hilling" is much better than "Taylor Swifting", the boys go to Café Monet, to film Cartman "faith hilling" in front of it. However, another group of children are already there "Taylor Swifting". Cartman interrupts them, standing in front of the camera. Later, after a brief disagreement about the merits of "Taylor Swifting" in comparison to "faith hilling", the situation devolves into a fight, resulting in the other group of children being put into the hospital.
Professor Lamont is seen once again telling the fourth grade class about the dangers of "memeing", however, this time, he uses a loaded pistol as an example. He places the pistol on Butters' desk, asking the class if they think that doing such is safe. After the class agrees that it is not safe, he demonstrates even further, forcing Butters to place the barrel of the gun in his mouth. Two men interrupt his demonstration, pulling him out of the classroom and asking for his help. They explain that cats are starting to meme by "cat breading". Professor Lamont is not surprised, explaining to them that humans have been "memeing" since the Egyptians. He says that, by memeing, cats are evolving and proving themselves to be nearly as intelligent as humans.
The boys, after briefly confronting Mr. Kitty for "cat breading", decided that they should go "faith hilling" at the Alcoholics Anonymous building. Kenny objects to this, saying that it is pointless, as "faith hilling is "out of style".
A news reporter is seen reporting on two deaths cause by a new meme called "Oh Long Johnsoning". The reporter reveals that a human did not start the meme, but a cat, who has been arrested for its part in the aforementioned deaths.
Stan is caught performing a combination of "Taylor Swifting" and "Oh Long Johnsoning" by the rest of the boys, who angrily criticize him. However, Kenny takes his side, resulting in Cartman having to prevent Kyle from attacking him.
Professor Lamont and the two agents are seen interrogating the arrested cat, who responds by repeatedly saying "Oh Long Johnson". Professor Lamont threatens the cats with war, but the cat refuses to respond.
Cartman and Kyle are seen "faith hilling" outside of a Planned Parenthood clinic, however, after various insults from others, they realize that "faith hilling" truly is out of style. Afterwards, a combined group of the boys and the other children are seen watching Cartman perform a combination of "Taylor Swifting", "Cat Breading", and "Reporting".
The boys are once again seen at a debate, attempting to perform the aforementioned combination of memes. However, Cartman stops, realizing conforming is not the correct thing to do, he begins to "faith hill" and sing about how it is the only meme he will ever do. The audience and Presidential candidates are amazed at the "quality" of his "faith hilling", resulting in them all "faith hilling" themselves. Another reporter is seen reporting on Cartman reminding everyone what "being human" means, however he says the message is unclear, but as long as the message has a celebrity bashing song with Republican "hopefuls" dancing around "faith hilling", it doesn't matter. He names this new meme "Pandering" shortly before he is hit by a train.