Chief Runs With Premise appeared in the Season Seven episode, "Red Man's Greed".
Chief Runs With Premise is a wealthy Native American who owns a large casino and is the main antagonist in the episode. He wants to buy and demolish South Park in order to build a super highway straight from Denver to the casino. He eventually wins South Park from them while gambling, but later has a change of heart and gives the townsfolk back their town.
Chief Runs With Premise wears a black two-piece suit with a white shirt and blue tie. His head garment is similar to that of a traditional Plains Indian feathered headdress. It symbolizes authority which is representative of the fact that he owns the casino that bought South Park.