地狱被撒旦统治，是一个几乎所有人死后要去的往生场所。在南方公园的早期剧集中，只有摩门教徒死后被送往天堂，所以所有在生前不是摩门教徒的人现在都住在地狱。包括希特勒，甘地，肯尼迪，杰夫瑞·达莫，吉恩·西斯克尔等许许多多的人。这种情况在天堂难以控制地狱大军时得到改变。肯尼作为一个罗马天主教徒至少去过两次天堂，肯尼也去过地狱。
南方公园中的地狱和传统的基督地狱很不一样。尽管地狱是个像个洞穴似的有火焰的地方，撒旦在背叛上帝后被送往这里享受永恒的痛苦，但无论地狱或者撒旦都不是纯粹的邪恶。撒旦总的来说是个容易相处，充满乐趣的人。他不怎么管地狱，除了时不时会举办圣诞派对或者夏威夷宴会。地狱里的人们建造家园，享受食物，很可能是地狱原产的食物——有一集展现了撒旦从熔岩湖中捕鱼。他们甚至似乎还做些生意，比如在第一次圣诞特辑中向杰夫瑞·达莫出售“节日圣诞火腿”的屠夫。
Death in Hell is meaningless, as anyone who dies in Hell is simply resurrected the next day, such as when Saddam Hussein and Chris killed each other over Satan's affections. This, in turn, results in the people and demons in Hell seemingly taking a different attitude towards pain and injury. Tiny black imps or other red devils are sometimes shown hurting or torturing humans, much to the carefree amusement of onlookers. Though most people in Hell are free to wander about and do whatever they like, there are a few people who are shown chained to walls. These people might be chained up simply on the whim of Satan or some other fallen angels, or it may be that they are being punished for some underworld infraction, irritating Satan, interfering with parties, etc. It is unlikely that they are being punished for something that they did in their lives on Earth, that sort of thing doesn't happen in the South Park Hell. It doesn't seem to matter who you were when you were alive; Hell treats you the same no matter what. People like Paul Bundy and Mother Theresa are often shown side-by-side, singing and drinking together at Satan's parties, and no famous criminal is ever shown with a specialized punishment for his or her sins.
There are several different types of demons seen there; most prominently small, black creatures with Canadian-esque heads that bounce around and squeal constantly, which Satan apparently used to take over the world in South Park: Bigger, Longer & Uncut. In "Best Friends Forever", new types of demons are seen, who are notably more detailed and intimidating, like Satan himself in that episode: They are large, red, humanoid creatures carrying over sized axes and swords. It seems demons in hell have some sort of immunity to Earth weaponry, yet are vulnerable to electricity, as shown when Cartman killed a demon with a single powerful electric shock in South Park: Bigger, Longer & Uncut. The reasons for this, if there are any, are so far unknown.
Hell seems to be resemble Dantes sixth circle of Heresy. Although, it is unknown if the producers intended this or if it is just a coincidence.
Prominence
- "The Mexican Staring Frog of Southern Sri Lanka"
- "Mr. Hankey's Christmas Classics"
- "Do the Handicapped Go to Hell?"
- "Probably"
- "Dead Celebrities"
- "Best Friends Forever"
- "Hell on Earth 2006"
South Park: Bigger, Longer & Uncut
Kenny is sent to Hell after accidentally catching himself on fire, and dying.