This page contains trivia for "Tonsil Trouble". Remember, trivia must be factual, provable, and it is always best to cite your source for not-so-obvious trivia. If you would like to dispute a trivia point, please discuss it in the article comments.
Cartman states that AIDS isn't funny even though AIDS had been officially declared funny in the episode "Jared Has Aides".
Kyle rips Clyde Frog's head off in this episode, killing him.
This episode may have been the creators' protest that many pharmaceutical companies have cut funding to research AIDS treatments, and how if a cure for AIDS was discovered then it would cost too much for people in places such as Africa (where AIDS is a major problem), who would not be able to afford the cure.
When Kyle tears the Mel Gibson poster apart, he was screaming in rage, which was only heard in the digital release of the episode and not on the original Comedy Central broadcast.
This episode features a new opening sequence. It begins with the camera zooming out of Stan's eye as the characters fall into place like in the original version. Then various clips from past episodes are played out like in the Season 6 - 11 opening. As the boys sing their lines, they move about across the screen while minimized clips are played out. The crowd scene is also redesigned and includes future atheists, The Lollipop King, and Jesse Jackson amongst others. The theme music remains the same as the one introduced in "Make Love, Not Warcraft".
As Kyle and Cartman enter the airport, a voice over the loudspeaker says "The white zone is for loading and unloading..." This is a reference to the opening scene of "Airplane!". The same line is also used in "Toy Story 2" when the toys arrive at the airport to save Woody from going to Japan.
Though not a direct allusion; the way Cartman contracts HIV in this episode is similar to how British actor Denholm Elliott (Best known for his role as Marcus Brody in the Indiana Jones series) contracted the disease himself, through a accidental transfusion of blood infected with HIV. Denholm died of AIDS-related tuberculosis in 1992.
Two brave little buddies who against all odds have journeyed across America to find a cure for AIDS; all they have is each other in a race against time." This is an allusion to the 1995 Brad Renfro film, The Cure.
In the episode "Red Sleigh Down", Kyle's cousin Kyle said if Cartman cured cancer and AIDS, he would still owe Santa two presents.
Cartman acknowledges how he has broken into Kyle's house many times before, something which he has not noted before despite having been seen numerous times, including "Casa Bonita".
Cartman squirts his blood into Kyle's mouth. Blood transfusions normally cause serious problems when not crossmatched, but Cartman has the same blood type as Kyle, as stated in "Cherokee Hair Tampons".
Also from "Cherokee Hair Tampons", Kyle did actually have a transfusion of sorts - he is currently using one of Cartman's kidneys.
Cartman's Xbox also reappears, having been seen previously in "Tsst".
Clyde Frog is also seen, having his head ripped off by an enraged Kyle, once again inferring Cartman's love of his stuffed toys.
A flag with a picture of a cow on it and the words "Cow Days" appears in Cartman's room. This is a reference to the South Park festival and episode entitled "Cow Days".
Cartman knows a lot about the exterior layout of the Broflovski house and says he has broken into Kyle's room a lot. In a previous episode, "Butt Out", he knew the interior layout well and tried to hammer boards over Kyle's door to keep him in.
One of the Visitors can be seen sitting by the table on the far left side in the celebration of the discovery of the remedy for AIDS, at the end of the episode.