It is revealed in The Fractured But Whole that Craig has had 4 guinea pigs named Stripe; the Stripe he has now (Stripe #4) was given to him by his boyfriend, Tweek, presumably because the other ones died or ran away.
Stripe #1 died when Craig's mom accidentally stepped on him, and broke his back.
Craig suspects his dad of poisoning Stripe #3 after he pooped in the dining room. It's also revealed that Stripe #3 died very recently, due to the fact that Craig still has (#3)'s toys and food dish tucked away in his closet.
Stripe's appearance frequently changes from the traditional construction paper art style to live-action. In the traditional style his torso and limbs are covered in dark brown fur, and the fur on his head is white with light brown splodges. He also has a pink nose.
In his live-action appearance his fur is primarily colored light brown, with a few white and ginger splodges here and there.
Craig sometimes dresses him up in a pirate costume.
- Exactly which Stripe (#1/#2/#3) Cartman and Craig are referring to in "Tweek vs. Craig" remains unknown.
- Stripe (#4)'s live action appearance looks identical to the Guinea Pirate from "Pandemic 2: The Startling".