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Season Twenty-One | Season Twenty-Two | Season Twenty-Three | 
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- Main article: List of Episodes
Officially announced on July 8, 2015[1], Season Twenty-Two premiered September 26, 2018.
Episodes
| Screenshot | Title | Air Date | Code | # |
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"Dead Kids" | September 26, 2018 | 2201 | 288 |
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Randy is desperate to help Sharon get her emotions under control and Cartman unexpectedly fails his math test. | ||||
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"A Boy And A Priest" | October 3, 2018 | 2202 | 289 |
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A very special relationship has developed between Butters and the Parish Priest. When the town finds the church doors locked and no sign of the pair, they call in the Catholic Church | ||||
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"The Problem with a Poo" | October 10, 2018 | 2203 | 290 |
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Mr. Hankey’s offensive behavior puts him in jeopardy of being fired as the Director of the Annual Christmas Pageant. | ||||
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"Tegridy Farms" | October 17, 2018 | 2204 | 291 |
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Butters is selling vape pens and all kinds of fruity-flavored vape accessories at school. Meanwhile, Randy decides he should move the family to the country and take up farming. | ||||
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"The Scoots" | October 31, 2018 | 2205 | 292 |
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The kids plan to use the latest revolution in mobility to get more candy on Halloween than they have ever gotten before. | ||||
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"Time To Get Cereal" | November 7, 2018 | 2206 | 293 |
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When dead citizens start popping up all over town, the boys realize they need Al Gore’s help. The boys are willing to do almost anything to save the town, and themselves, but it may be just too late. | ||||
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"Nobody Got Cereal?" | November 14, 2018 | 2207 | 294 |
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The boys break out of jail and are on the run from the police and ManBearPig. | ||||
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"Buddha Box" | November 28, 2018 | 2208 | 295 |
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Cartman just can’t deal with people any longer. They get in the way of what’s most important in his life. | ||||
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"Unfulfilled" | December 5, 2018 | 2209 | 296 |
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The citizens of South Park are enjoying all the perks of being a company town when the Amazon Fulfillment Center moves in. Everything is just swell until the contradictions inherent in capitalism threaten to bring down the entire system down. | ||||
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"Bike Parade" | December 12, 2018 | 2210 | 297 |
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Despite the chaos at the Amazon Fulfillment Center, the Bike Parade is still on. The boys’ chance of winning is in jeopardy when Kenny resists commercialism in solidarity with the striking workers. | ||||
| Season Twenty-Two | ||||