When the school bus becomes perilously trapped on the edge of a cliff, the driver Ms. Crabtree, searches for help. She finds the highway and hitch hikes a ride from a semi-truck driver named Mitch, who resembles Elvis Presley in speech and mannerisms. Together they travel around the USA visiting comedy clubs and late night talk shows as Ms. Crabtree becomes a sensation in the stand-up comedy field.
- Roofies are street slang for animal tranquilizers used by veterinarians.
- Elvis Presley was a delivery truck driver before he became famous as a musician.