She first appears in "Cartman's Mom is Still a Dirty Slut" as the only nurse at Hells Pass Hospital. She helps keep the kids informed of what's going on while the Doctor works. This is her only major appearance, but she can be seen with (likely prosthetic) arms in South Park: Bigger, Longer & Uncut and "Cartman Joins NAMBLA" in Kenny's dream sequence.
She has red hair has long eyelashes. She wears scrubs and lipstick, but she lost her arms, using her mouth to fill the void.