Mark or Marc may refer to several people in the South Park continuity:
- Mark the security guard - A minor character who appeared in "Korn's Groovy Pirate Ghost Mystery" and "Trapper Keeper".
- Mark Cotswolds - A home-schooled kid who appeared in "Hooked on Monkey Phonics".
- Mark - A member of Skyler's band who appeared in "Cat Orgy" and "Timmy 2000".
- Muscleman Marc - One of Cartman's toys, who is killed in "1%".
- Mark Cotner - A minor character who appeared in "The Wacky Molestation Adventure".
- Mark Harrison - One of Gary Harrison's brothers who appeared in "All About Mormons".
- Enchorito Mark - A minor character who was killed in the game South Park: The Stick of Truth.
The following celebrities named Mark have appeared on South Park.
- Mark Fuhrman - A racist "ni-gger-guy" who helps Randy in "With Apologies to Jesse Jackson".
- Mark McGwire - A former baseball player and athlete accused of using steroids in "Up the Down Steroid".
- Mark Zuckerberg - The founder of Facebook who appeared in "Franchise Prequel".
The following people named Marc have worked on the production of South Park.