The Mackey Residence is Mr. Mackey's home. The outside briefly appeared in the Season Two episode, "Ike's Wee Wee" but the rest of the house was shown in the Season Three episode, "Two Guys Naked in a Hot Tub". It also appeared in the Season Twenty-Two episodes "Tegridy Farms", with a new navy color, and "The Scoots".
Mr. Mackey's house is built just like every other house in South Park. The house was colored a red-brownish color, but in "Tegridy Farms" the house, including the garage, has a completely new look, being colored in navy. He had three connected mailboxes outside, something that was never seen before on the other houses in South Park. His garden has a Hot Tub on the decking.
Mr. Mackey's house has a front room on the first floor large enough to host parties in. On the second floor his bedroom and presumably a bathroom exist. His basement is also shown, there's likely more than one room as the one shown has a door leading into it rather than stairs.
- "Ike's Wee Wee" - Mr. Mackey is evicted after losing his job.
- "Cat Orgy" - Liane is briefly seen at the party here.
- "Two Guys Naked in a Hot Tub" - The meteor shower party happens here.
- "Mr. Hankey's Christmas Classics" - Mr. Mackey sings Carol of the Bells outside here.
- "Skank Hunt" - Scott Malkinson calls Mr. Mackey up to say he wants to quit Twitter.
- "Tegridy Farms" - Kyle comes here to talk to Mr. Mackey about vaping, only to find Cartman and Butters there as well.
- "The Scoots" - Mr. Mackey is haunted by the E-Scooters.