Kim, Kourtney, and Khloé Kardashian are three sisters that star on the show Keeping Up with the Kardashians. They first appeared in the episode "The Tale of Scrotie McBoogerballs".
Despite their shallowness, it's a complete hit, and even Butters Stotch finds himself enamored by the three girls, especially Kim, who he states he wants to "jump on her belly".
When the boys read The Catcher in the Rye for a class assignment, they find it horribly disappointing as a "controversial" story, they opt to write their own The Tales of Scrotie McBoogerballs and proceed to make it as vulgar as possible for the sake of vulgarity. However, afraid of getting in trouble when their parents find it, they switch the blame to Butters, who gains instant celebrity status, as the book becomes a massive hit. Butters proceeds to then write The Poop That Took a Pee, which is a childish sequel to the previous book, but like the first becomes an instant success.
However, the second book somehow causes a reader to believe to kill all the "phonies" which to him means killing the Kardashians. He then travels to where the show is being filmed and brutally shoots all three sisters, along with Bruce and Kris Jenner, with a 12-gauge pump-action shotgun.
This causes Butters' career as an author to abruptly end, and both his book and the book that the boys wrote both become banned. He is left completely devastated over the fact that they were murdered because of him.
Although they are murdered, the Kardashians make a cameo return in the episode "200", in which they join with other celebrities in a plot against South Park.
In "The Hobbit", it has been confirmed that they have somehow been resurrected, as Kim Kardashian is now Kanye West's fiancée. It is also revealed that Kim Kardashian apparently has many striking similarities to a hobbit, in terms of appearance and lifestyle. Kim is also criticized by Wendy Testaburger as a product of Photoshop. According to her, Kim Kardashian is a short, overweight "Hobbit", causing her to be called "jelly" by Mr. Mackey, and threatening to send her to "Jelly School".
Caitlyn Jenner, formerly Bruce Jenner, made her debut at the beginning of Season 19 and was one of the main focuses in the season. A running gag throughout the season was Caitlyn Jenner running over and killing lots of people with her car, referring to when Bruce Jenner had a car accident in June 2015. The character somehow revived and came back into South Park as Caitlyn Jenner.