Big Tobacco Co. is a cigarette factory that appears in Season Seven episode "Butt Out".
Background[]
In an attempt to sabotage the Big Tobacco company business, Rob Reiner (disguised as a woman named "Rita Poon") takes the boys to the factory and get its executive to tour them around the factory. During the tour, they were shown the cigarette-making process, while the workers sing "Cigarettes All Hidey Lidey Day". Rob Reiner then took a photo of the boys in the factory and called the executive out for being "Reinered". The group then hurried their way out of the factory, with Reiner killing a worker in the process.
Rob Reiner later gathered the townspeople outside the factory with torches, demand the supposed release of the boys from the factory. However, as Reiner revealed that he had intended to kill Cartman in order to push his anti-smoking agenda, the townspeople turned against him instead, before being killed by Cartman instead.