Taming Strange/Trivia

References to Popular Culture

 * IntelliLink is a reference to the problems associated with the Obamacare website, Healthcare.gov.
 * Mr. Mackey's computer plays Lionel Richie's "All Night Long" and Glenn Frey's "The Heat is On".
 * Foofa's decision of appealing more to adult audiences is reminiscent of Miley Cyrus; Foofa's performance at the MTV Video Music Awards also reflects Miley Cyrus' controversial performance at the 2013 VMA.
 * A Bieber World Tour poster can be see in the background when the Yo Gabba Gabba characters are talking to Ike about his behavior on stage.
 * Ike's diuretic medication was switched with New England Patriots Quarterback Tom Brady's hormone medication.
 * Two cover lines on Rolling Stone read, "The Last Days of NIRVANA: Yep, we're still talking about them." and "Eddie Vedder (Yep, him, too)", criticising how often Rolling Stone publishes articles about Nirvana and Eddie Vedder, who is the lead singer and rhythm guitarist of Pearl Jam.
 * In the end, Ike is seen watching Dora the Explorer on television.
 * Ike was chewing Skoal Straight tobacco in this episode.

Continuity

 * Ike Broflovski confronts Kyle about his game, "Kick the baby!", a popular catchphrase from the earlier episodes.
 * The queef bit is a reference back to "Eat, Pray, Queef".
 * The Canadian Healthcare video also references the buddy/guy/friend bit from "Canada on Strike".
 * This is the second episode where one of the children takes hormones, albeit unknowingly. Stan first takes hormones in "Are You There God? It's Me, Jesus", in order to go through puberty after believing his friends are going through it.